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腦多巴胺神經(jīng)營養(yǎng)因子抗體免 疫 原；KLH conjugated synthetic peptide derived from human ARMETL1: 101-187/187
維甲酸調(diào)節(jié)核基質(zhì)相關(guān)蛋白抗體注意事項(xiàng)；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Tissue specificity: Expressed in placenta and testis, very low expression seen in skeletal muscle. Detected in all hematopoietic tissues examined, with highest expression in thymus and bone marrow. A low level detected in the spleen and lymph node, and barely detectable level in the peripheral leukocytes. RA treatment down-regulated the expression in NT2 cell. Function: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.
芳香烴受體核轉(zhuǎn)錄蛋白2抗體免 疫 原；KLH conjugated synthetic peptide derived from human ARNT2: 351-450/717
尾側(cè)型同源轉(zhuǎn)錄因子1抗體注意事項(xiàng)；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: Could play a role in the terminal differentiation of the intestine.
肌動蛋白相關(guān)蛋白2/3亞型4抗體免 疫 原；KLH conjugated synthetic peptide derived from human ARPC4/p20-ARC: 1-100/168
尾型同源盒轉(zhuǎn)錄因子4抗體注意事項(xiàng)；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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