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簡(jiǎn)要描述:細(xì)胞膜鈣ATP酶4抗體免 疫 原;KLH conjugated synthetic peptide derived from human PMCA4: 901-1000/1241
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細(xì)胞膜鈣ATP酶4抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
細(xì)胞膜鈣ATP酶4抗體 | PMCA4 | GOY-01K2039 |
商品屬性:
英文名稱: PMCA4
中文名:細(xì)胞膜鈣ATP酶4抗體
別 名;MXRA 1; MXRA1;
Plasma membrane calcium ATPase 4; Plasma membrane calcium ATPase isoform 4;
Plasma membrane calcium pump isoform 4; Plasma membrane calcium transporting
ATPase 4; Plasma membrane calcium-transporting ATPase 4; PMCA 4; PMCA4; PMCA-4;
PMCA4b; PMCA4x; Sarcolemmal calcium pump; AT2B4_HUMAN; ATP2B2; ATP2B4; ATPase
Ca++ transporting plasma membrane 4; DKFZp686G08106; DKFZp686M088; Matrix
remodelling associated 1; Matrix remodelling associated protein 1;
Matrix-remodeling-associated protein 1
抗體來(lái)源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Horse, Rabbit, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;138kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human PMCA4: 901-1000/1241
<Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;Preservative:
15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Plasma membrane-type Ca2+-ATPases (PMCAs) mediate
the export of bivalent calcium ions from eukaryotic cells. As members of the
P class of ion-motive ATPases, PMCAs are a functionally diverse group of
proteins that are derived from alternatively spliced transcripts originating
from four distinct genes, PMCA1, 2, 3, and 4. The expression of different
PMCA isoforms and splice variants is regulated in a developmental, tissue-
and cell type-specific manner, and with respect to the physiological needs of
specific cell and tissue types. Spatial and temporal rates of resting
intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are
dependent on the array of PMCA isoforms that are expressed in concert with
the rate of Ca2+ export. PMCA3 expression is confined to brain and skeletal
muscle. The PMCA4 gene is located on human chromosome 1q25 and is
ubiquitously expressed. This magnesium-dependent enzyme catalyzes the
hydrolysis of ATP coupled with the transport of calcium out of the cell. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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