簡(jiǎn)要描述:核因子活化T細(xì)胞胞漿蛋白2抗體免 疫 原;KLH conjugated synthetic peptide derived from human NFATc2: 451-550/925
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核因子活化T細(xì)胞胞漿蛋白2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
核因子活化T細(xì)胞胞漿蛋白2抗體 | NFAT1 | GOY-01K0924 |
商品屬性:
英文名稱: NFAT1
中文名:核因子活化T細(xì)胞胞漿蛋白2抗體
別 名;NFATc2; AI607462;
KIAA0611; NF ATp; NF-ATc2; NFAT 1; NFAT pre existing subunit; NFAT
transcription complex, preexisting component; NFAT1; NFAT1-D; NFATc2; NFATp;
Nuclear factor of activated T cells cytoplasmic 2; Nuclear factor of activated
T cells cytoplasmic calcineurin dependent 2; Nuclear factor of activated T
cells pre-existing component; T cell transcription factor NFAT; NF2IP_HUMAN;
Nuclear factor of activated T-cells, cytoplasmic 2; NFAT pre-existing subunit;
NF-ATp; T-cell transcription factor NFAT1.
研究領(lǐng)域;腫瘤 心血管 免疫學(xué) 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 t-淋巴細(xì)胞
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse,
)
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;100kDa
細(xì)胞定位;細(xì)胞核 細(xì)胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human NFATc2: 451-550/925
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene is a member of the nuclear factor of
activated T cells (NFAT) family. The product of this gene is a DNA-binding
protein with a REL-homology region (RHR) and an NFAT-homology region (NHR).
This protein is present in the cytosol and only translocates to the nucleus
upon T cell receptor (TCR) stimulation, where it becomes a member of the
nuclear factors of activated T cells transcription complex. This complex
plays a central role in inducing gene transcription during the immune
response. Alternate transcriptional splice variants encoding different
isoforms have been characterized. [provided by RefSeq, Apr 2012] Plays a role in the inducible expression of
cytokine genes in T-cells, especially in the induction of the IL-2, IL-3,
IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation
of GPC6 expression and WNT5A signaling pathway. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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