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簡(jiǎn)要描述：人單純皰疹病毒Ⅰ型神經(jīng)毒性因子ICP34.5抗體免 疫 原；KLH conjugated synthetic peptide derived from HHV1, strain F Neurovirulence factor ICP34.5: 101-200/263
產(chǎn)品型號(hào)：GOY-01K0270廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問(wèn) 量：155產(chǎn)品分類
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人單純皰疹病毒Ⅰ型神經(jīng)毒性因子ICP34.5抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
人單純皰疹病毒Ⅰ型神經(jīng)毒性因子ICP34.5抗體 | Neurovirulence factor ICP34.5 | GOY-01K0270 |
商品屬性：
英文名稱: Neurovirulence factor ICP34.5
中文名:人單純皰疹病毒Ⅰ型神經(jīng)毒性因子ICP34.5抗體
別 名；ICP34_HHV1F;
Neurovirulence factor ICP34.5; Infected cell protein 34.5; protein
gamma(1)34.5; RL1; ICP34.5; Human alphaherpesvirus 1 strain F; HHV1;
研究領(lǐng)域；細(xì)胞生物 細(xì)菌及病毒
抗體來(lái)源；Rabbit
克隆類型；Polyclonal
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；27kDa
細(xì)胞定位；細(xì)胞核 細(xì)胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from HHV1, strain F Neurovirulence factor
ICP34.5: 101-200/263
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Herpes simplex type 1 (HSV-1) belongs to a family
that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken
pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to
distinguish from each other. Members of this family have a characteristic
virion structure. The double stranded DNA genome is contained within an
icosahedral capsid embedded in a proteinaceous layer (tegument) and
surrounded by a lipid envelope, derived from the nuclear membrane of the last
host, which is decorated with virus-specific glycoproteins spikes. These
viruses are capable of entering a latent phase where the host shows no
visible sign of infection and levels of infectious agent become very low.
During the latent phase the viral DNA is integrated into the genome of the
host cell. Contributes to HSV resistance to the antiviral
effects of alpha/beta interferon. Recruits the serine/threonine-protein
phosphatase PPP1CA/PP1-alpha to dephosphorylate the translation initiation
factor eIF-2A, thereby couteracting the host shutoff of protein synthesis
involving double-stranded RNA-dependent protein kinase EIF2AK2/PKR. Also
down-modulates the host MHC class II proteins cell surface expression. Acts
as a neurovirulence factor that has a profound effect on the growth of the
virus in central nervous system tissue, probably through its ability to
maintain an environment favorable for viral replication. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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