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二磷酸腺苷核糖基化因子6相互作用蛋白抗體
產品名稱 | 英文名稱 | 貨號 |
二磷酸腺苷核糖基化因子6相互作用蛋白抗體 | ARL6 | GOY-01K0305 |
商品屬性:
英文名稱: ARL6
中文名:二磷酸腺苷核糖基化因子6相互作用蛋白抗體
別 名;ADP ribosylation
factor like 6; ADP ribosylation factor like protein 6; ADP-ribosylation
factor-like protein 6; Arl6; ARL6_HUMAN; Bardet Biedl syndrome 3 protein;
Bardet-Biedl syndrome 3 protein; BBS3; MGC32934.
研究領域;細胞生物 信號轉導 細胞凋亡 G蛋白信號
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應;(predicted:
Human, Mouse, Rat, Horse, )
產品應用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;20kDa
細胞定位;細胞漿 細胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human ARL6: 31-120/186
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
The protein encoded by this gene belongs to the
ARF family of GTP-binding proteins. ARF proteins are important regulators of
cellular traffic and are the founding members of an expanding family of
homologous proteins and genomic sequences. They depart from other small
GTP-binding proteins by a unique structural device that implements front-back
communication from the N-terminus to the nucleotide-binding site. Studies of
the mouse ortholog of this protein suggest an involvement in protein
transport, membrane trafficking, or cell signaling during hematopoietic
maturation. Alternative splicing occurs at this locus and two transcript
variants encoding the same protein have been described. [provided by RefSeq,
Jul 2008]. Involved in membrane protein trafficking at the
base of the ciliary organelle. Mediates recruitment onto plasma membrane of
the BBSome complex which would constitute a coat complex required for sorting
of specific membrane proteins to the primary cilia. May regulate cilia
assembly and disassembly and subsequent ciliary signaling events such as the
Wnt signaling cascade. Isoform 2 may be required for proper retinal function
and organization. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結果是陽性。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務,包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yǎng)、抗體修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體定制服務:
已注冊商標,主要用于抗體藥物發(fā)現和開發(fā),是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務,主要面向工業(yè)客戶。
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