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半乳糖轉(zhuǎn)移酶7亞基β1,4抗體

簡(jiǎn)要描述:半乳糖轉(zhuǎn)移酶7亞基β1,4抗體免 疫 原;KLH conjugated synthetic peptide derived from human B4GALT7: 201-300/327

  • 產(chǎn)品型號(hào):GOY-01K1006
  • 廠商性質(zhì):科研
  • 更新時(shí)間:2023-10-24 00:00:00
  • 訪  問  量:519

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半乳糖轉(zhuǎn)移酶7亞基β1,4抗體


產(chǎn)品名稱

英文名稱

貨號(hào)

半乳糖轉(zhuǎn)移酶7亞基β1,4抗體

B4GALT7

GOY-01K1006

商品屬性:

英文名稱: B4GALT7

中文名:半乳糖轉(zhuǎn)移酶7亞基β1,4抗體

    名;B4GAL T7; Beta 1,4 galactosyltransferase 7; Beta 1,4 GalTase 7; Beta4Gal T7; UDP Gal:beta GlcNAc beta 1,4 galactosyltransferase 7; XGALT 1; XGALT1; XGPT1; Xylosylprotein beta 1,4 galactosyltransferase, polypeptide 7; B4GT7_HUMAN.

研究領(lǐng)域;細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  細(xì)胞分化  細(xì)胞骨架  細(xì)胞外基質(zhì)

抗體來源;Rabbit

克隆類型;Polyclonal

交叉反應(yīng);(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )

產(chǎn)品應(yīng)用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復(fù))

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理論分子量;37kDa

細(xì)胞定位;細(xì)胞漿 細(xì)胞膜

    狀;Liquid

    度;1mg/ml

免 疫 原;KLH conjugated synthetic peptide derived from human B4GALT7: 201-300/327

    型;IgG

純化方法;affinity purified by Protein A

緩 沖 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事項(xiàng);This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產(chǎn)品介紹:

β-1,4-galactosyltransferases (β-1,4-Gal-T) are type II membrane-bound glycoproteins that are  substrate-specific and function to transfer galactose in a β-1,4 linkage to an acceptor sugar. There are seven members of the β-1,4-Gal-T family, all of which are directed to the golgi  apparatus through a hydrophobic sequence at the N-terminus. β-1,4-Gal-T7, also known as B4GALT7 or XGALT1, is a 327 amino acid  single-pass type II membrane protein that is expressed at high levels in  heart, pancreas and liver. β-1,4-Gal-T7 uses  manganese to catalyze the UDP-dependent biosynthesis of glycosphingolipids.  The gene encoding β-1,4-Gal-T7 is mutated in  Ehlers-Danlos syndrome progeroid type (EDSP), a variant form of Ehlers-Danlos  syndrome characterized by progeroid facies, mild mental retardation, short  stature, skin hyperextensibility, moderate skin fragility, joint  hypermobility principally in digits.β-1,4-galactosyltransferases  (β-1,4-Gal-T) are type II membrane-bound  glycoproteins that are substrate-specific and function to transfer galactose  in a -1,4 linkage to an acceptor sugar. There are  seven members of the β-1,4-Gal-T family, all of which  are directed to the golgi apparatus through a hydrophobic sequence at the  N-terminus. β-1,4-Gal-T7, also known as B4GALT7 or  XGALT1, is a 327 amino acid single-pass type II membrane protein that is  expressed at high levels in heart, pancreas and liver. β-1,4-Gal-T7 uses manganese to catalyze the UDP-dependent  biosynthesis of glycosphingolipids. The gene encoding β-1,4-Gal-T7 is mutated in Ehlers-Danlos syndrome progeroid type  (EDSP), a variant form of Ehlers-Danlos syndrome characterized by progeroid  facies, mild mental retardation, short stature, skin hyperextensibility,  moderate skin fragility, joint hypermobility principally in  digits.-1,4-galactosyltransferases (β-1,4-Gal-T) are  type II membrane-bound glycoproteins that are substrate-specific and function  to transfer galactose in a -1,4 linkage to an  acceptor sugar. There are seven members of the β-1,4-Gal-T  family, all of which are directed to the golgi apparatus through a  hydrophobic sequence at the N-terminus. β-1,4-Gal-T7,  also known as B4GALT7 or XGALT1, is a 327 amino acid single-pass type II  membrane protein that is expressed at high levels in heart, pancreas and  liver. β-1,4-Gal-T7 uses manganese to catalyze the  UDP-dependent biosynthesis of glycosphingolipids. The gene encoding β-1,4-Gal-T7 is mutated in Ehlers-Danlos syndrome progeroid type  (EDSP), a variant form of Ehlers-Danlos syndrome characterized by progeroid  facies, mild mental retardation, short stature, skin hyperextensibility,  moderate skin fragility, joint hypermobility principally in digits.

Required for the biosynthesis of the  tetrasaccharide linkage region of proteoglycans, especially for small  proteoglycans in skin fibroblasts.

 

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多克隆抗體制備:

我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。

鼠單克隆抗體制備:

客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。

圖片1.png

重組抗體表達(dá)服務(wù):

重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。

單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):

我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。

抗體定制服務(wù):

已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。

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