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腦組織表達(dá)X連鎖蛋白1抗體

簡(jiǎn)要描述:腦組織表達(dá)X連鎖蛋白1抗體免 疫 原;KLH conjugated synthetic peptide derived from human HBEX2/Bex1: 55-125/125

  • 產(chǎn)品型號(hào):GOY-01K1595
  • 廠(chǎng)商性質(zhì):科研
  • 更新時(shí)間:2023-10-24 00:00:00
  • 訪(fǎng)  問(wèn)  量:533

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腦組織表達(dá)X連鎖蛋白1抗體


產(chǎn)品名稱(chēng)

英文名稱(chēng)

貨號(hào)

腦組織表達(dá)X連鎖蛋白1抗體

Bex1

GOY-01K1595

商品屬性:

英文名稱(chēng): Bex1

中文名:腦組織表達(dá)X連鎖蛋白1抗體

   名;BEX2; Brain expressed X linked 1; HBEX2; Protein BEX1; BEX1_HUMAN.

研究領(lǐng)域;腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)

抗體來(lái)源;Rabbit

克隆類(lèi)型;Polyclonal

交叉反應(yīng);(predicted: Human, Mouse, Rat, Cow, Rabbit, )

產(chǎn)品應(yīng)用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理論分子量;15kDa

細(xì)胞定位;細(xì)胞核 細(xì)胞漿

   狀;Liquid

   度;1mg/ml

原;KLH conjugated synthetic peptide derived from human HBEX2/Bex1: 55-125/125

   型;IgG

純化方法;affinity purified by Protein A

液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事項(xiàng);This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產(chǎn)品介紹:

The brain-expressed X-linked (Bex) family of proteins is expressed in the central nervous system, with highest levels detected in cerebellum, temporal lobe and pituitary tissues. Bex1 plays an important role in neuronal differentiation in response to nerve growth factor (NGF), as well as in cell cycle progression. Bex1 is a highly ubiquitinated protein and acts as a link between the cell cycle and neurotrophic factor signaling. Bex2 interacts with LMO2, thereby regulating the transcriptional activity of a DNA-binding complex. Bex1 and Bex 2 are widely expressed outside of the central nervous system with high expression in the liver. Bex1 and Bex2 shuttle between the cytoplasm and the nucleus. Though the role of Bex1 is largely unknown, it may function by coordinating internal cellular states with the ability of cells to respond to external signals.

] Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity).

 

 

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多克隆抗體制備:

我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶(hù)節(jié)約成本。

鼠單克隆抗體制備:

客戶(hù)可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專(zhuān)業(yè)的建議。在制備過(guò)程中,與客戶(hù)互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿(mǎn)足客戶(hù)抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶(hù)節(jié)約成本。

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重組抗體表達(dá)服務(wù):

重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶(hù)提供各種類(lèi)型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。

單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):

我公司也為客戶(hù)提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。

抗體定制服務(wù):

已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶(hù)量身定制的專(zhuān)業(yè)服務(wù),主要面向工業(yè)客戶(hù)。

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