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簡要描述：5-氨基乙酰丙酸合酶1抗體免疫原：KLH conjugated synthetic peptide derived from human ALAS2/ALAS-E
產(chǎn)品型號(hào)：GOY-01K4173廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：214產(chǎn)品分類
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5-氨基乙酰丙酸合酶1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
5-氨基乙酰丙酸合酶1抗體 | ALAS-E | GOY-01K4173 |
商品屬性：
英文名稱: ALAS-E
中文名:5-氨基乙酰丙酸合酶1抗體
英文別名 ：5-aminolevulinate
synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase;
ALAS E; ALASE; ANH1; Delta aminolevulinate synthase; XLSA; 5 aminolevulinic
acid synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase;
5-aminolevulinate synthase 2; Alas 2; ALAS; ALAS E; ALAS, erythroid; ALASE;
Aminolevulinate, delta-, synthase 2; Aminolevulinic acid synthase 2, erythroid;
ANH1; ASB; Delta ALA synthase 2; Delta ALA synthetase; Delta aminolevulinate
synthase 2; Delta aminolevulinate synthase; Erythroid specific ALAS; FLJ93603;
XLDPP; XLSA.
交叉反應(yīng) ：Human,
Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
標(biāo)記 ：Unconjugated
抗體來源：Rabbit
抗體類型：Polyclonal
免疫原：KLH
conjugated synthetic peptide derived from human ALAS2/ALAS-E
蛋白細(xì)胞定位：細(xì)胞漿
純化方法：affinity
purified by Protein A
亞型：IgG
性狀：Liquid
濃度：1mg/ml
儲(chǔ)存液：0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件：Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
背景資料5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS,
an enzyme catalyzing the first step of the heme biosynthetic pathway in
mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of
hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a
housekeeping protein which mediates synthesis of early heme in the mitochondria
of most cells. Succinyl CoA associates with ALAS-E in protein conformation
change and translocation of ALAS-E into the mitochondria and does not interact
with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear
activators such as GATA-1, NF-E2 and EKLF. Since the ALAS e maps to the X
chromosome, mutation of the e leads to the pyridoxine-refractory X-linked
sideroblastic anemia.
產(chǎn)品介紹:
5-aminolevulinate synthase 1 (ALAS-H) and 2
(ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the
heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme,
ALAS-E, regulates the first step of hematopoietic cell differentation and
iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates
synthesis of early heme in the mitochondria of most cells. Succinyl CoA
associates with ALAS-E in protein conformation change and translocation of
ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E
5'-flanking region contains binding sites for nuclear activators such as
GATA-1, NF-E2 and EKLF. Since the ALAS e maps to the X chromosome, mutation
of the e leads to the pyridoxine-refractory X-linked sideroblastic anemia. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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