簡(jiǎn)要描述:雌激素受體α抗體免疫原 KLH conjugated synthetic peptide derived from human Estro Receptor alpha
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雌激素受體α抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
雌激素受體α抗體 | Estro receptor alpha | GOY-01K0066 |
商品屬性:
英文名稱: Estro receptor alpha
中文名:雌激素受體α抗體
英文名稱:Estro
receptor alpha
英文別名 Estradiol
receptor; Estro receptor alpha; Estradiol Receptor-alpha; Estro Receptor 1;
Atherosclerosis, susceptibility to, included; DKFZp686N23123; ER Alpha; ER;
ER-alpha; ERalpha; ER[a]; Era; ESR; ESR1; ESR1_HUMAN; ESR2; ESRA; Estr; Estro
receptor 1 (alpha); Estro resistance, included; HDL cholesterol, augmented
response of, to hormone replacement, included; Myocardial infarction,
susceptibility to, included; NR3A1; Nuclear receptor subfamily 3 group A member
1; OTTHUMP00000017718; OTTHUMP00000017719; RNESTROR.
交叉反應(yīng):Human,
Mouse, Rat
標(biāo)記:Unconjugated
抗體來源: Rabbit
抗體類型:Polyclonal
免疫原 KLH
conjugated synthetic peptide derived from human Estro Receptor alpha
蛋白細(xì)胞定位: 細(xì)胞核
純化方法: affinity
purified by Protein A
亞型 IgG
性狀: Liquid
濃度: 1mg/ml
儲(chǔ)存液: 0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件: Shipped
at 4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
研究領(lǐng)域: 腫瘤 免疫學(xué) 生長(zhǎng)因子和激素
產(chǎn)品介紹:
Estro and progesterone receptor are members of a
family of transcription factors that are regulated by the binding of their
cognate ligands. The interaction of hormone-bound estro receptors with estro
responsive elements(EREs) alters transcription of ERE-containing es. The
carboxy terminal region of the estr receptor contains the ligand binding
domain, the amino terminus serves as the transactivation domain, and the DNA
binding domain is centrally located. Two forms of estro receptor have been
identified, ER Alpha and ER Beta. ER Alpha and ER Beta have been shown to be
differentially activated by various ligands. The biological response to
progesterone is mediated by two distinct forms of the human progesterone
receptor (hPR-A and hPR-B), which arise from alternative splicing. In most
cells, hPR-B functions as a transcriptional activator of
progesterone-responsive e, whereas hPR-A function as a transcriptional
inhibitor of all steroid hormone receptors. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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