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簡要描述：內質網(wǎng)Aβ相關結合蛋白抗體免 疫 原；KLH conjugated synthetic peptide derived from human ERAB: 51-130/196
產(chǎn)品型號：GOY-01K1532廠商性質：科研更新時間：2023-10-24 00:00:00訪 問 量：202產(chǎn)品分類
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內質網(wǎng)Aβ相關結合蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
內質網(wǎng)Aβ相關結合蛋白抗體 | ERAB/HSD17B10 | GOY-01K1532 |
商品屬性：
英文名稱: ERAB/HSD17B10
中文名:內質網(wǎng)Aβ相關結合蛋白抗體
別 名；HSD17B10;
Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase; 17 beta hydroxysteroid
dehydrogenase 10; 17 beta hydroxysteroid dehydrogenase type 10; 17b HSD10; 3
hydroxy 2 methylbutyryl CoA dehydrogenase; 3 hydroxyacyl CoA dehydrogenase type
2; 3 hydroxyacyl CoA dehydrogenase type II; AB binding alcohol dehydrogenase;
ABAD; Ads9; Amyloid beta binding polypeptide; Amyloid beta peptide binding
alcohol dehydrogenase; Amyloid beta peptide binding protein; CAMR; DUPXp11.22;
Endoplasmic Reticulum Amyloid Binding Protein; Endoplasmic reticulum associated
amyloid beta peptide binding protein; ER associated amyloid beta-binding
protein; ERAB; HADH 2; HADH2; HCD 2; HCD2; HSD17B10; Hydroxyacyl CoA
Dehydrogenase type II; Hydroxyacyl Coenzyme A dehydrogenase type II;
Hydroxysteroid (17 beta) dehydrogenase 10; Mental retardation X linked
syndromic 11; MHBD; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase;
Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; MRPP2;
MRX17; SCHAD; SDR5C1; Short chain dehydrogenase/reductase family 5C member 1;
Short chain L 3 hydroxyacyl CoA dehydrogenase type 2; Short chain type
dehydrogenase/reductase XH98G2; Type 10 17b HSD; Type 10 17beta hydroxysteroid
dehydrogenase; Type II HADH; XH98G2.
研究領域；免疫學 神經(jīng)生物學 線粒體
抗體來源；Mouse
克隆類型；Polyclonal
交叉反應； (predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, )
產(chǎn)品應用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；21kDa
細胞定位；細胞漿 線粒體
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ERAB: 51-130/196
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene encodes 3-hydroxyacyl-CoA dehydrogenase
type II, a member of the short-chain dehydrogenase/reductase superfamily. The
gene product is a mitochondrial protein that catalyzes the oxidation of a
wide variety of fatty acids, alcohols, and steroids. The protein has been
implicated in the development of Alzheimer's disease, and mutations in the
gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency
(MHBD). Several alternatively spliced transcript variants have been
identified, but the full-length nature of only two transcript variants has
been determined. [provided by RefSeq, Jul 2008]. Functions in mitochondrial tRNA maturation. Part
of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1,
MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their
5'-ends. By interacting with intracellular amyloid-beta, it may contribute to
the neuronal dysfunction associated with Alzheimer disease (AD). |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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