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TRIM27蛋白抗體
產品名稱 | 英文名稱 | 貨號 |
TRIM27蛋白抗體 | TRIM27 | GOY-01K5115 |
商品屬性：
英文名稱: TRIM27
中文名:TRIM27蛋白抗體
別 名；AW538890;
DAAP-182E11.3; MGC189472; OTTHUMP00000029314; RET finger protein; RFP; RFP
transforming protein; Rfp1; RING finger protein 76; RNF76; TRI27_HUMAN; TRIM
27; Trim27; Tripartite motif containing 27; Tripartite motif containing protein
27; Tripartite motif protein TRIM27; Tripartite motif-containing protein 27;
Zinc finger protein RFP.
研究領域；腫瘤 細胞生物 轉錄調節(jié)因子 鋅指蛋白 表觀遺傳學
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Cow, Rabbit, )
產品應用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；58kDa
細胞定位；細胞核 細胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human TRIM27: 65-160/513
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
This gene encodes a member of the tripartite motif
(TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a
B-box type 1 and a B-box type 2, and a coiled-coil region. This protein
localizes to the nuclear matrix. It interacts with the enhancer of polycomb
protein and represses gene transcription. It is also thought to be involved
in the differentiation of male germ cells. Fusion of the N-terminus of this
protein with the truncated C-terminus of the RET gene product has been shown
to result in production of the ret transforming protein. [provided by RefSeq,
Jul 2008] Has a transcriptional repressor activity by
cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase
and p38 kinase and also increases caspase-3-like activity independently of
mitochondrial events. May function in male germ cell development. Has
DNA-binding activity and preferentially bound to double-stranded DNA (By
similarity). E3 ubiquitin-protein ligase that mediates ubiquitination of
PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'-linked
polyubiquitin chains; the function inhibits CD4 T-cell activation. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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