簡要描述:睪丸特異激酶2抗體免 疫 原;KLH conjugated synthetic peptide derived from Human TESK2: 301-400/571
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睪丸特異激酶2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
睪丸特異激酶2抗體 | TESK2 | GOY-01K1131 |
商品屬性:
英文名稱: TESK2
中文名:睪丸特異激酶2抗體
別 名;Dual specificity
testis specific protein kinase 2; Dual specificity testis-specific protein
kinase 2; MGC29168; OTTHUMP00000009093; RP23-109A3.2; Tesk2; TESK2_HUMAN;
Testicular protein kinase 2; Testis specific kinase 2.
研究領(lǐng)域;細胞生物 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) 干細胞 激酶和磷酸酶 細胞骨架
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Chicken, Horse, Rabbit, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;64kDa
細胞定位;細胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from Human TESK2: 301-400/571
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
?TESK2 is a nuclear protein that belongs to the
protein kinase superfamily and is expressed in testis and prostate.
Functioning as a dual-specificity protein kinase, TESK2 catalyzes the
ATP-dependent phosphorylation of substrates and autophosphorylation on
tyrosine and serine/threonine residues, thereby mediating intracellular
signal transduction pathways. TESK2 requires magnesium as a cofactor and its
catalytic activity is thought to play an important role in meiotic events
such as spermatogenesis. TESK2 contains one protein kinase domain that is 65%
identical to the kinase domain found in TESK1 (testicular protein kinase 1),
suggesting a similar role for these proteins in phosphorylation events. Three
isoforms of TESK2 are expressed due to alternative splicing. Dual specificity protein kinase activity
catalyzing autophosphorylation and phosphorylation of exogenous substrates on
both serine/threonine and tyrosine residues. Phosphorylates cofilin at
'Ser-3'. May play an important role in spermatogenesis. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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