簡(jiǎn)要描述:脫髓鞘相關(guān)蛋白SH3TC2N抗體免 疫 原;KLH conjugated synthetic peptide derived from human SH3TC2: 851-950/1288
產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
脫髓鞘相關(guān)蛋白SH3TC2N抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
脫髓鞘相關(guān)蛋白SH3TC2N抗體 | SH3TC2 | GOY-01K4341 |
商品屬性:
英文名稱: SH3TC2
中文名:脫髓鞘相關(guān)蛋白SH3TC2N抗體
別 名;KIAA1985; CMT4C;
D430044G18Rik; FLJ13605; MNMN; PP12494; RGD1309038; S3TC2_HUMAN; SH3 domain and
tetratricopeptide repeats-containing protein 2; SH3TC2.
研究領(lǐng)域;免疫學(xué) 神經(jīng)生物學(xué)
抗體來(lái)源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;145kDa
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human SH3TC2: 851-950/1288
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
SH3TC2 (SH3 domain and tetratricopeptide repeats
2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR
repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of
peripheral nerves, and localized to the plasma membrane and to the
perinuclear endocytic recycling compartment, suggesting a possible function
in myelination and/or in regions of axoglial interactions. The SH3TC2 protein
is expressed in adult heart, testis, spinal cord, and brain as well as in
fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is
caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth
disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or
compound heterozygous mutation in the SH3TC2 gene. Existing as four
alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is
conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and
maps to human chromosome 5q32. Strongly expressed in brain and spinal cord.
Expressed at equal level in spinal cord and sciatic nerve. Weakly expressed
in striated muscle. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
產(chǎn)品咨詢
歡迎您關(guān)注我們的微信了解更多信息
電話
微信掃一掃