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簡(jiǎn)要描述:跨膜蛋白SEMA4B抗體免 疫 原;KLH conjugated synthetic peptide derived from human SEMA4B: 165-210/832
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跨膜蛋白SEMA4B抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
跨膜蛋白SEMA4B抗體 | SEMA4B | GOY-01K2282 |
商品屬性:
英文名稱: SEMA4B
中文名:跨膜蛋白SEMA4B抗體
別 名;Sema domain
immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic
domain (semaphorin) 4B; Sema domain immunoglobulin domain (Ig) transmembrane
domain (TM) and short cytoplasmic domain 4B; SEMA4B; SEMAC; Semaphorin 4B;
SemC; KIAA1745; MGC131831; SEM4B_HUMAN.
研究領(lǐng)域;細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞分化
抗體來(lái)源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other
applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;88kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human SEMA4B: 165-210/832
<Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Semaphorins are a family of cell surface and
secreted proteins that are conserved from insects to humans. Members of this
family of proteins are approximately 750 amino acids in length (including
signal sequences) and are defined by a conserved extracellular “semaphorin” domain of
approximately 500 amino acids containing 14-16 cysteines, blocks of conserved
sequences and no obvious repeats. The transmembrane semaphorins are
characterized by an additional 80 amino acid transmembrane domain and an
80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins
chemically attract and repel the growth of neural axons, guiding the
development of intricate networks of neural tissue. SEMA4B (semaphorin-4B),
also known as SemC or SEMAC, is an 832 amino acid single-pass type I membrane
protein that belongs to the semaphorin family and exists as two alternatively
spliced isoforms. Containing one Ig-like C2-type (immunoglobulin-like)
domain, a PSI domain and a single sema domain, SEMA4B is encoded by a gene
located on human chromosome 15. SEMA4B belongs to the semaphorin family and
contains 1 Ig-like C2-type (immunoglobulin-like) domain, 1 PSI domain and 1
Sema domain. It inhibits axonal extension by providing local signals to
specify territories inaccessible for growing axons. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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