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簡要描述:電壓門控鈉離子通道型α4抗體免 疫 原;KLH conjugated synthetic peptide derived from human SCN4A: 301-400/1836
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電壓門控鈉離子通道型α4抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
電壓門控鈉離子通道型α4抗體 | SCN4A | GOY-01K5270 |
商品屬性:
英文名稱: SCN4A
中文名:電壓門控鈉離子通道型α4抗體
別 名;HYKPP; HYPP;
Na(V)1.4; NAC1A; Nav1.4; Scn4a; SCN4A_HUMAN; Skeletal muscle voltage dependent
sodium channel type IV alpha subunit; SkM1; Sodium channel protein skeletal
muscle subunit alpha; Sodium channel protein type 4 subunit alpha; Sodium
channel protein type IV subunit alpha; Sodium channel voltage gated type IV
alpha subunit; Voltage gated sodium channel subunit alpha Nav1.4; Voltage gated
sodium channel type 4 alpha; Voltage-gated sodium channel subunit alpha Nav1.4.
研究領(lǐng)域;免疫學(xué) 神經(jīng)生物學(xué) 通道蛋白 跨膜蛋白
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Cow, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;208kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human SCN4A: 301-400/1836
<Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Voltage-gated sodium channels are transmembrane
glycoprotein complexes composed of a large alpha subunit with 24
transmembrane domains and one or more regulatory beta subunits. They are
responsible for the generation and propagation of action potentials in
neurons and muscle. This gene encodes one member of the sodium channel alpha
subunit gene family. It is expressed in skeletal muscle, and mutations in
this gene have been linked to several myotonia and periodic paralysis
disorders. [provided by RefSeq, Jul 2008] This protein mediates the voltage-dependent sodium
ion permeability of excitable membranes. Assuming opened or closed
conformations in response to the voltage difference across the membrane, the
protein forms a sodium-selective channel through which Na(+) ions may pass in
accordance with their electrochemical gradient. This sodium channel may be
present in both denervated and innervated skeletal muscle. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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