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簡要描述：干燥綜合征相關(guān)蛋白2抗體免 疫 原；KLH conjugated synthetic peptide derived from human TROVE-2/SSA2: 331-430/538
產(chǎn)品型號：GOY-01K2325廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：163產(chǎn)品分類
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干燥綜合征相關(guān)蛋白2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
干燥綜合征相關(guān)蛋白2抗體 | RO60 | GOY-01K2325 |
商品屬性：
英文名稱: RO60
中文名:干燥綜合征相關(guān)蛋白2抗體
別 名；TROVE2; TROVE 2;
TROVE-2; 60 kDa ribonucleoprotein Ro; 60 kDa Ro protein; 60 kDa SS A/Ro
ribonucleoprotein; 60 kDa SS-A/Ro ribonucleoprotein; Autoantigen Ro/SSA, 60-KD;
bA101E13.2; Gastric cancer multi drug resistance protein; Ribonucleoprotein
autoantigen SS A/Ro; RO 60; Ro 60 kDa autoantigen; RO60_HUMAN; RoRNP; Sjoegren
syndrome antigen A2; Sjoegren syndrome type A antigen; Sjogren syndrome antigen
A2 (60kD ribonucleoprotein autoantigen SS A/Ro); Sjogren syndrome antigen A2
(60kDa ribonucleoprotein autoantigen SS A/Ro); Sjogren syndrome antigen A2; SS
A; SS-A; SS-A/Ro; SSA 2; SSA; SSA2; TROVE domain family member 2; TROVE2.
研究領(lǐng)域；細(xì)胞生物 免疫學(xué) 表觀遺傳學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；61kDa
細(xì)胞定位；細(xì)胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human TROVE-2/SSA2: 331-430/538
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Ro autoantigens are of clinical significance
because antibodies directed against them are found in most patients with
primary Sjqgren syndrome, subacute cutaneous lupus erythematosus (SLE),
neonatal lupus erythematosus, ANA-negative lupus erythematosus, and systemic
lupus erythematosus-like disease secondary to homozygous C2 or C4 complement
deficiency (1). Ro/SSA is a ribonucleoprotein that binds to autoantibodies in
35 to 50% of patients with SLE and in up to 97% of patients with Sjqgren
syndrome (2). The Ro/SSA particle consists of a single immunoreactive protein
noncovalently bound with one of four small RNA molecules (2). Most
anti-Ro/SSA-positive sera antibodies detect not only the main protein, but
also a smaller Ro/SSA protein (2). The genes which encode the smaller and
larger proteins map to human chromosomes 11p15.5 and 1q31, respectively (3?).
La/SSB is an autoimmune RNA-binding protein that plays a role in the
transcription of RNA polymerase III was originally defined by its reactivity
with autoantibodies from patients with Sj鰃ren syndrome and SLE (6). RNA-binding protein that binds to several small
cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from
degradation. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進(jìn)行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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