簡要描述:環(huán)指蛋白185抗體免 疫 原;KLH conjugated synthetic peptide derived from human RNF185: 1-100/192
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環(huán)指蛋白185抗體
產品名稱 | 英文名稱 | 貨號 |
環(huán)指蛋白185抗體 | RNF185 | GOY-01K0541 |
商品屬性:
英文名稱: RNF185
中文名:環(huán)指蛋白185抗體
別 名;FLJ38628; Ring
finger protein 185; RN185_HUMAN.
研究領域;細胞生物 免疫學
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應;(predicted:
Human, Mouse, Rat, Chicken, Horse, Sheep, )
產品應用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;20kDa
細胞定位;細胞漿 細胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human RNF185: 1-100/192
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
The RING-type zinc finger motif is present in a
number of viral and eukaryotic proteins and is made of a conserved
cysteine-rich domain that is able to bind two zinc atoms. Proteins that
contain this conserved domain are generally involved in the ubiquitination
pathway of protein degradation. RNF185 (ring finger protein 185), also known
as FLJ38628, is a 192 amino acid multi-pass membrane protein containing one
RING-type zinc finger. Two RNF185 isoforms exist as a result of alternative
splicing, and the gene encoding RNF185 maps to human chromosome 22, which
houses over 500 genes and is the second smallest human chromosome. Mutations
in several of the genes that map to chromosome 22 are involved in the
development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and
schizophrenia. Mitochondrial E3 ubiquitin-protein ligase that
regulatesselective mitochondrial autophagy by mediating
'Lys-63'-linkedpolyubiquitination of BNIP1. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結果是陽性。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務,包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yǎng)、抗體修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體定制服務:
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務,主要面向工業(yè)客戶。
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