簡要描述:Rab溶酶體相互作用蛋白樣2抗體免 疫 原;KLH conjugated synthetic peptide derived from human RILPL2: 111-211/211
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Rab溶酶體相互作用蛋白樣2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
Rab溶酶體相互作用蛋白樣2抗體 | RILPL2 | GOY-01K0257 |
商品屬性:
英文名稱: RILPL2
中文名:Rab溶酶體相互作用蛋白樣2抗體
別 名;FLJ30380;
FLJ32372; MGC7036; p40phox-binding protein; Rab-interacting lysosomal
protein-like 2; RILP-like protein 2; RILPL2; RIPL2_HUMAN; RLP2; Rab interacting
lysosomal protein-like 2.
研究領(lǐng)域;細胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細胞骨架 G蛋白信號
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;24kDa
細胞定位;細胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human RILPL2: 111-211/211
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
RILPL2 is a 211 amino acid protein that belongs to
the RILPL family. RILPL2 does not regulate lysosomal morphology or
distribution. RILPL2 shares 32% and 18% amino acid identity with RILPL1 and
RILP, respectively. RILPL2 as a novel interacting partner for the actin-based
molecular motor MyoVa, and has a novel role for RILPL2 in controlling
neuronal morphogenesis. It has been suggested that there is also a novel role
for RILPL2 in the regulation of cellular shape and dendritic-spine
morphogenesis, probably via the Rac1-Pak pathway. PCR analysis of human
tissues detects highest RILPL2 expression in lung, followed by placenta.
Lower expression is detected in liver, kidney, pancreas, heart and brain, but
no expression is detected in skeletal muscle. The RILPL2 gene is conserved in
chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human
chromosome 12q24.31. Involved in cell shape and neuronal morphogenesis,
positively regulating the establishment and maintenance of dendritic spines.
May activate RAC1 |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務(wù),包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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