簡(jiǎn)要描述:RAGEF2蛋白抗體免 疫 原;KLH conjugated synthetic peptide derived from human RAGEF2: 601-700/1601
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RAGEF2蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
RAGEF2蛋白抗體 | RAGEF2 | GOY-01K4639 |
商品屬性:
英文名稱: RAGEF2
中文名:RAGEF2蛋白抗體
別 名;DKFZp667N084; DKFZp686I15116;
KIA001LB; PDZ domain containing guanine nucleotide exchange factor (GEF) 2; PDZ
domain containing guanine nucleotide exchange factor 2; PDZ domain containing
guanine nucleotide exchange factor I; PDZ domain-containing guanine nucleotide
exchange factor 2; PDZ GEF 2; PDZ GEF2; PDZ-GEF2; PDZGEF 2; PDZGEF2; RA GEF 2;
RA GEF2; RA-GEF-2; RAGEF 2; Rap guanine nucleotide exchange factor (GEF) 6; Rap
guanine nucleotide exchange factor 2; Rap guanine nucleotide exchange factor 6;
RAPGEF6; RPGF6_HUMAN.
研究領(lǐng)域;細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) 跨膜蛋白
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Rabbit, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;179kDa
細(xì)胞定位;細(xì)胞漿 細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human RAGEF2: 601-700/1601
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
RAPGEF6 is a guanine nucleotide exchange factor
(GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm
and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains
an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding
domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a
Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins
exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6
is capable of binding to M-Ras via its RA domain. Due to alternative splicing
events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and
PDZ-GEF2B. Guanine nucleotide exchange factor (GEF) for
Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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