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簡要描述:原鈣粘附蛋白α5抗體免 疫 原;KLH conjugated synthetic peptide derived from human PCDHA5: 351-250/936
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原鈣粘附蛋白α5抗體
產品名稱 | 英文名稱 | 貨號 |
原鈣粘附蛋白α5抗體 | PCDHA5 | GOY-01K2013 |
商品屬性:
英文名稱: PCDHA5
中文名:原鈣粘附蛋白α5抗體
別 名;Cadherin related
neuronal receptor 6; CNR 6; CNR6; CNRN 6; CNRN6; CNRS 6; CNRS6; CRNR 6; CRNR6;
Ortholog of mouse CNR6; PCDH alpha5; PCDHA 5; Protocadherin alpha 5;
PCDA5_HUMAN.
研究領域;神經生物學 信號轉導 細胞粘附分子 細胞骨架 細胞外基質 細胞膜蛋白
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應;(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;99kDa
細胞定位;細胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human PCDHA5: 351-250/936
<Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
Protocadherins are a large family of cadherin-like
cell adhesion proteins that are involved in the establishment and maintenance
of neuronal connections in the brain. There are three protocadherin gene
clusters, designated alpha, beta and gamma, all of which contain multiple
tandemly arranged genes. PCDHA5 (Protocadherin alpha-5) is one of fifteen
members of the protocadherin alpha protein family that is expressed in
neurons. PCDHA5 is a 936 amino acid single-pass type I membrane protein
containing 6 cadherin domains. Localized to the cell membrane, PCDHA5
functions as a calcium-dependent cell-adhesion protein that is present in
synaptic junctions and is essential to the establishment and maintenance of
certain cell-cell interactions. PCDHA5 is expressed as 3 isoforms produced by
alternative splicing. Function: Potential calcium-dependent cell-adhesion protein.
May be involved in the establishment and maintenance of specific neuronal
connections in the brain. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達到1:32000,由蛋白抗原制備的多抗,保證WB檢測結果是陽性。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時,也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價,按節(jié)點收費,為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺,能為客戶提供各種類型的重組抗體表達服務,包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達,抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務,如動物免疫、動物飼養(yǎng)、抗體修飾服務(如FITC,HRP等的標記)、以及ELISA,WB,IHC,DB等檢測服務。
抗體定制服務:
已注冊商標,主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務,主要面向工業(yè)客戶。
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