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原鈣粘附蛋白11Y/11X抗體
產品名稱 | 英文名稱 | 貨號 |
原鈣粘附蛋白11Y/11X抗體 | PCDH11Y + PCDH11X | GOY-01K2263 |
商品屬性：
英文名稱: PCDH11Y + PCDH11X
中文名:原鈣粘附蛋白11Y/11X抗體
別 名；PCDH 11; PCDH
11X; PCDH 11Y; PCDH 22; PCDH PC; PCDH Y; PCDH11; PCDH11X; PCDH22; PCDHY;
Protocadherin 11; Protocadherin 11 X linked; Protocadherin 11 Y linked;
Protocadherin 22; Protocadherin on the Y chromosome; Protocadherin PC;
Protocadherin prostate cancer; Protocadherin Y; Protocadherin11;
Protocadherin22; ProtocadherinY; PC11Y_HUMAN; PCDH11; PCDH22; PCDHX; PCDHY;
Protocadherin 11; Protocadherin 11 X linked; Protocadherin 11 Y linked;
Protocadherin 22; Protocadherin on the X chromosome; Protocadherin on the Y
chromosome; Protocadherin PC; Protocadherin prostate cancer; PC11X_HUMAN.
研究領域；腫瘤 神經生物學 細胞粘附分子 細胞骨架 細胞膜蛋白
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；Human, (predicted: Mouse, Rat, Pig, Cow, Horse,
Rabbit, Sheep, )
產品應用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；144kDa
細胞定位；細胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human PCDH11Y: 81-180/1340
<Extracellular>
亞 型；IgG
純化方法；affinity
purified by Protein A
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
This gene belongs to the protocadherin gene
family, a subfamily of the cadherin superfamily. The encoded protein consists
of an extracellular domain containing 7 cadherin repeats, a transmembrane
domain and a cytoplasmic tail that differs from those of the classical
cadherins. The gene is located in a major X/Y block of homology and its Y
homolog, despite divergence leading to coding region changes, is the most
closely related cadherin family member. The protein is thought to play a
fundamental role in cell-cell recognition essential for the segmental
development and function of the central nervous system. Transcripts arising
from alternative splicing encode isoforms with variable cytoplasmic domains.
[provided by RefSeq, Jul 2008]. Function: PCDH11Y (Protocadherin 11 Y-linked) is a member of
the protocadherin family. Protocadherins constitute the largest subgroup
within the cadherin family of calcium-dependent cell-cell adhesion molecules.
Their specific functions are unknown but they may be involved in the
establishment and function of specific neuronal connections in the brain. The
PCDH11Y gene is located in a major X/Y block of homology and its most closely
related cadherin superfamily member is located in this homologous region on
the X chromosome (PCDH11X). |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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