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簡(jiǎn)要描述：轉(zhuǎn)錄因子OTX1抗體免 疫 原；KLH conjugated synthetic peptide derived from human OTX1: 1-100/354
產(chǎn)品型號(hào)：GOY-01K1918廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：164產(chǎn)品分類
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轉(zhuǎn)錄因子OTX1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
轉(zhuǎn)錄因子OTX1抗體 | OTX1 | GOY-01K1918 |
商品屬性：
英文名稱: OTX1
中文名:轉(zhuǎn)錄因子OTX1抗體
別 名；Homeobox protein
OTX 1; Homeobox protein OTX1; MGC15736; Orthodenticle 1; Orthodenticle homeobox
1; Orthodenticle homolog 1; Orthodenticle1; Otx 1; otx1; OTX1_HUMAN.
研究領(lǐng)域；神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；37kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human OTX1: 1-100/354
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Transcription factors, OTX1 and OTX2, are two
murine homologs of the Drosophila orthodenticle (OTD), show a limited amino
acid sequence divergence. OTX1 and OTX2 play an important role during early
and later events required for proper brain development in that they are
involved in the processes of induction, specification and regionalization of
the brain. OTX1 is involved in corticogenesis, sensory organ development and
pituitary functions, while OTX2 is necessary earlier in development, for the
correct anterior neural plate specification and organization of the primitive
streak. OTX2 is also required in the early specification of the
neuroectoderm, which is destined to become the fore-midbrain, and both OTX1
and OTX2 co-operate in patterning the developing brain through a
dosage-dependent mechanism. A molecular mechanism depending on a precise
threshold of OTX proteins is necessary for the correct positioning of the
isthmic region and for anterior brain patterning. The genes which encode OTX1
and OTX2 map to human chromosomes 2p15 and 14q21-q22, respectively. Function: Probably plays a role in the development of the
brain and the sense organs. Can bind to the BCD target sequence (BTS):
5'-TCTAATCCC-3'. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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