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簡要描述:利鈉肽受體A抗體免 疫 原;KLH conjugated synthetic peptide derived from human Natriuretic Peptide Receptor A: 261-360/1061
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利鈉肽受體A抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
利鈉肽受體A抗體 | Natriuretic Peptide Receptor A | GOY-01K0259 |
商品屬性:
英文名稱: Natriuretic Peptide Receptor A
中文名:利鈉肽受體A抗體
別 名;NPRA; ANP A;
ANP-A; ANPa; ANPR-A; ANPRA; ANPRA_HUMAN; Atrial natriuretic peptide A type
receptor; Atrial natriuretic peptide receptor 1; Atrial natriuretic peptide
receptor A; Atrial natriuretic peptide receptor type A; Atrionatriuretic
peptide receptor A; GC A; GC-A; Guanylate cyclase A; Guanylate cyclase; GUC2A;
GUCY2A; Natriuretic peptide A type receptor; Natriuretic peptide receptor
A/guanylate cyclase A; NPR 1; NPR A; NPR-A; NPR1; NPRA.
研究領(lǐng)域;心血管 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);Mouse, (predicted: Human, Rat, )
產(chǎn)品應(yīng)用;IHC-P=1:100-500
IHC-F=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;113kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human Natriuretic Peptide Receptor A:
261-360/1061 <Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Guanylyl cyclases, catalyzing the production of
cGMP from GTP, are classified as soluble and membrane forms (Garbers and
Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed
guanylyl cyclases A through F, form a family of cell-surface receptors with a
similar topographic structure: an extracellular ligand-binding domain, a
single membrane-spanning domain, and an intracellular region that contains a
protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B
function as receptors for natriuretic peptides; they are also referred to as
atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961).
Also see NPR3 (MIM 108962), which encodes a protein with only the
ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a
membrane-bound guanylate cyclase that serves as the receptor for both atrial
and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295),
respectively).[supplied by OMIM, May 2009] Receptor for the atrial natriuretic peptide
NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent
vasoactive hormones playing a key role in cardiovascular homeostasis. Has
guanylate cyclase activity upon binding of the ligand. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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