簡要描述:肌肉特異性環(huán)指蛋白2抗體免 疫 原;KLH conjugated synthetic peptide derived from human MURF2: 65-160/548
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肌肉特異性環(huán)指蛋白2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
肌肉特異性環(huán)指蛋白2抗體 | MURF2 | GOY-01K4228 |
商品屬性:
英文名稱: MURF2
中文名:肌肉特異性環(huán)指蛋白2抗體
別 名;MURF 2; MURF-2;
MuRF2; Muscle specific ring finger 2; Muscle specific RING finger protein 2;
Muscle-specific RING finger protein 2; ring finger protein 29; RNF 29; RNF29;
TRI55_HUMAN; TRIM 55; Trim55; Tripartite motif containing 55; Tripartite motif
containing protein 55; Tripartite motif-containing protein 55.
研究領(lǐng)域;細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 表觀遺傳學(xué)
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;60kDa
細(xì)胞定位;細(xì)胞核 細(xì)胞漿
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human MURF2: 65-160/548
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
MuRF1 (RNF28), MuRF2 (RNF29) and MuRF3 (RNF30) are
a specific class of RING finger proteins expressed in striated muscle tissues
that act as signaling molecules and cytoskeletal adaptors. The MuRF proteins
contain a conserved N-terminal RING domain and zinc-binding B-box motif in
addition to two coiled-coil motifs in their central regions. In muscle cells,
MuRF2 regulates gene expression and protein turnover. It localizes to the
cytoplasm, but under atrophic conditions it is detected in the nucleus. MuRF2
can form oligomers with various other proteins, including titin and myosin,
during sarcomere assembly. Endogenous MuRF2 associates with the sarcomeric
M-band in cardiomyocytes. There are at least four isoforms of MuRF2. Homooligomer and heterooligomer (Probable).
Interacts with titin/TTN. Interacts with myosins. Interacts with SQSTM1 and
NBR1. Isoform 4 may not able to interact with isoform 1, isoform 2 and
isoform 3. Probably interacts with TRIM63 and TRIM54. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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