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簡要描述：活化B淋巴細(xì)胞因子1抗體免 疫 原；KLH conjugated synthetic peptide derived from mouse MSC/Musculin: 51-150/201
產(chǎn)品型號：GOY-01K5450廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：154產(chǎn)品分類
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活化B淋巴細(xì)胞因子1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
活化B淋巴細(xì)胞因子1抗體 | MSC/Musculin | GOY-01K5450 |
商品屬性：
英文名稱: MSC/Musculin
中文名:活化B淋巴細(xì)胞因子1抗體
別 名；ABF-1; ABF1;
Activated B cell factor 1; Activated B-cell factor 1; bHLHa22; Class A basic
helix-loop-helix protein 22; Msc; MUSC_HUMAN; Musculin; MYOR.
研究領(lǐng)域；細(xì)胞生物 免疫學(xué) 淋巴細(xì)胞 b-淋巴細(xì)胞 表觀遺傳學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Guinea Pig, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；21kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from mouse MSC/Musculin: 51-150/201
亞 型；IgG
純化方法；affinity purified
by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Differentiation of myogenic cells is regulated by
multiple positively and negatively acting factors. One well characterized
family of helix-loop-helix (HLH) proteins, known to play an important role in
the regulation of muscle cell development, includes Myo D, myogenin and
musculin (also designated MyoR). Members of this group of transcription
factors form heterodimers with products of a more widely expressed family of
bHLH genes, the E family, which consists of at least three distinct genes:
E2A, IF2 and HEB. Myo D-E or musculin-E heterodimers bind avidly to consensus
E box motifs, which are functionally important elements in the promoter
regions of many muscle-specific terminal differentiation genes. Myo D
complexes potently induce transcriptional activation, while musculin complexes
bind adjacent to Myo D DNA-binding regions to represses Myo D activity, which
then results in the delayed expression of muscle-specific genes. Musculin is
highly expressed in undifferentiated and proliferating myoblasts in culture,
and its expression is down regulated during myogenesis and at the onset of
terminal differentiation. Transcription repressor capable of inhibiting the
transactivation capability of TCF3/E47. May play a role in regulating
antigen-dependent B-cell differentiation. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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