簡要描述:棕櫚?;さ鞍?抗體免 疫 原;KLH conjugated synthetic peptide derived from human MPP7: 301-400/576
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棕櫚?;さ鞍?抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
棕櫚?;さ鞍?span lang="EN-US">7抗體 | MPP7 | GOY-01K4647 |
商品屬性:
英文名稱: MPP7
中文名:棕櫚?;さ鞍?span lang="EN-US">7抗體
別 名;FLJ32798; MAGUK
p55 subfamily member 7; Membrane protein palmitoylated 7 MAGUK p55 subfamily
member 7; Palmitoylated membrane protein 7.
研究領(lǐng)域;腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞膜蛋白
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;65kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human MPP7: 301-400/576
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The MAGUK (membrane-associated guanylate kinase
homologs) family of proteins contain multiple protein-binding domains and are
involved in cell junction organization, tumor suppression, and signaling. The
MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like
and LIN2-like. MPP7 (MAGUK p55 subfamily member 7), also known as
palmitoylated membrane protein 7, is a 576 amino acid protein that belongs to
the MAGUK family and assists in the assembly of protein complexes. A
peripheral membrane protein that exists as a heterodimer, MPP7 enhances tight
junction formation and epithelial cell polarity. MPP7 contains one SH3
domain, a guanylate kinase-like domain, two L27 domains and a single PDZ
(DHR) domain. The gene encoding MPP7 maps to human chromosome 10p11.23 Function: MPP7 is a membrane-associated guanylate kinases
(MAGUKs), which are important adaptor proteins involved in the assembly of
protein complexes at sites of cell-cell contact. They are found in synapses,
adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ
domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains,
which are involved in multimerization of MAGUKs. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報價,按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
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已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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