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簡要描述：著絲粒蛋白X抗體免 疫 原；KLH conjugated synthetic peptide derived from human MHF2/CENPX: 1-60/81
產(chǎn)品型號：GOY-01K5808廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：143產(chǎn)品分類
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著絲粒蛋白X抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
著絲粒蛋白X抗體 | MHF2/CENPX | GOY-01K5808 |
商品屬性：
英文名稱: MHF2/CENPX
中文名:著絲粒蛋白X抗體
別 名；CENP X; CENP-X;
CENPX; CENPX_HUMAN; Centromere protein X; FAAP10; FANCM interacting histone
fold protein 2; FANCM-interacting histone fold protein 2; Fanconi anemia
associated polypeptide of 10 kDa; Fanconi anemia-associated polypeptide of 10
kDa; MGC14480; Retinoic acid inducible gene D9 protein homolog; Retinoic
acid-inducible gene D9 protein homolog; Stimulated by retinoic acid gene 13
protein homolog; STRA13.
研究領(lǐng)域；細胞生物 免疫學 結(jié)合蛋白 表觀遺傳學
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Cow, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；9kDa
細胞定位；細胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human MHF2/CENPX: 1-60/81
亞 型；IgG
純化方法；affinity
purified by Protein A
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human, therapeutic
or diagnostic applications.
產(chǎn)品介紹:
CENP-X is an 81 amino acid protein that functions
as a DNA-binding component of the FA complex for genome maintenance and DNA
damage repair. Localizing to chromatin in nucleus and centromere, Stra13
plays a role in muscle integrity by protecting muscle cells from oxidative
damage, and Stra13 overexpression has been shown to produce oxidative damage
resistance in mice. Stra13 undergoes alternative splicing events to produce
three isoforms which are encoded by a gene that maps to human chromosome 17
and mouse chromosome 11. Stra13 plays a role in assembly of the outer
kinetchore and is considered a target for myoepithelial cells and metastatic
tumors. Function: DNA-binding component of the FA core complex
involved in DNA damage repair and genome maintenance. Recruited to forks
stalled by DNA interstrand cross-links, and required for cellular resistance
to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that
binds and supercoils DNA, and plays an important role in kinetochore
assembly. Component of the APITD1/CENPS complex that is essential for the
stable assembly of the outer kinetochore. Plays an important role in mitotic
progression and chromosome segregation. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務(wù)。
單項免疫學及檢測服務(wù):
我公司也為客戶提供單項免疫學和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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