簡要描述:NK細(xì)胞抑制性受體2DS3抗體免 疫 原;KLH conjugated synthetic peptide derived from human KIR2DS3: 61-160/304
產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
NK細(xì)胞抑制性受體2DS3抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
NK細(xì)胞抑制性受體2DS3抗體 | KIR2DS3 | GOY-01K5214 |
商品屬性:
英文名稱: KIR2DS3
中文名:NK細(xì)胞抑制性受體2DS3抗體
別 名;KI2S3_HUMAN;
Killer cell immunoglobulin-like receptor 2DS3; KIR2DS3; MHC class I NK cell
receptor; Natural killer-associated transcript 7; NKAT-7; NKAT7.
研究領(lǐng)域;細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 自然殺傷細(xì)胞
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;31kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human KIR2DS3: 61-160/304
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Killer cell immunoglobulin-like receptors (KIRs)
are transmembrane glycoproteins expressed by natural killer cells and subsets
of T cells. The KIR genes are polymorphic and highly homologous and they are found
in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex
(LRC). The gene content of the KIR gene cluster varies among haplotypes,
although several "framework" genes are found in all haplotypes
(KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the
number of extracellular immunoglobulin domains (2D or 3D) and by whether they
have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long
cytoplasmic domain transduce inhibitory signals upon ligand binding via an
immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the
short cytoplasmic domain lack the ITIM motif and instead associate with the
TYRO protein tyrosine kinase binding protein to transduce activating signals.
The ligands for several KIR proteins are subsets of HLA class I molecules;
thus, KIR proteins are thought to play an important role in regulation of the
immune response. [provided by RefSeq, Jul 2008] Receptor on natural killer (NK) cells for HLA-C
alleles. Does not inhibit the activity of NK cells. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
產(chǎn)品咨詢
歡迎您關(guān)注我們的微信了解更多信息
電話
微信掃一掃