歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！
咨詢(xún)電話(huà)：18321818584歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！咨詢(xún)電話(huà)：18321818584
簡(jiǎn)要描述：KDEL受體抗體免 疫 原；KLH conjugated synthetic peptide derived from human KDEL Receptor: 151-212/212
產(chǎn)品型號(hào)：GOY-01K0452廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問(wèn) 量：132產(chǎn)品分類(lèi)
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
KDEL受體抗體
產(chǎn)品名稱(chēng) | 英文名稱(chēng) | 貨號(hào) |
KDEL受體抗體 | KDEL Receptor | GOY-01K0452 |
商品屬性：
英文名稱(chēng): KDEL Receptor
中文名:KDEL受體抗體
別 名；ER lumen protein
retaining receptor 1; ERD 2; ERD2; ERD2.1; ERD21_HUMAN; ERD21; HDEL; KDEL (Lys
Asp Glu Leu) endoplasmic reticulum protein retention receptor 1; KDEL
(Lys-Asp-Glu-Leu) 72 kD endoplasmic reticulum protein retention receptor 1;
KDEL endoplasmic reticulum protein retention receptor 1; KDEL R1; KDEL receptor
1; KDELR 1; KDELR1; PM 23; PM23; Putative MAPK activating protein PM23.
研究領(lǐng)域；細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞類(lèi)型標(biāo)志物
抗體來(lái)源；Rabbit
克隆類(lèi)型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；25kDa
細(xì)胞定位；細(xì)胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human KDEL Receptor: 151-212/212
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Retention of resident soluble proteins in the
lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal
cells by their continual retrieval from the cis-Golgi, or a pre-Golgi
compartment. Sorting of these proteins is dependent on a C-terminal
tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and
his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a
receptor that recognizes, and binds the tetrapeptide-containing protein, and
returns it to the ER. In yeast, the sorting receptor encoded by a single
gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several
human homologs of the ERD2 gene, constituting the KDEL receptor gene family,
have been described. The protein encoded by this gene was the first member of
the family to be identified, and it encodes a protein structurally and
functionally similar to the yeast ERD2 gene product. Required for the retention of luminal endoplasmic
reticulum resident proteins via vesicular recycling. This receptor recognizes
the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in
the form of round vesicles or as tubular processes, mediate retrograde traffic
of the KDEL receptor-ligand complexes. Also required for normal vesicular
traffic through the Golgi. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶(hù)節(jié)約成本。
鼠單克隆抗體制備:
客戶(hù)可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專(zhuān)業(yè)的建議。在制備過(guò)程中，與客戶(hù)互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿(mǎn)足客戶(hù)抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶(hù)節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶(hù)提供各種類(lèi)型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶(hù)提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶(hù)量身定制的專(zhuān)業(yè)服務(wù)，主要面向工業(yè)客戶(hù)。
產(chǎn)品咨詢(xún)
聯(lián)系人：銷(xiāo)售部
地址：上海市嘉定區(qū)澄瀏公路52號(hào)盛創(chuàng)企業(yè)
郵箱：3004918891@qq.com
手機(jī)：18321818584 / 15026555973歡迎您關(guān)注我們的微信了解更多信息
掃一掃電話(huà)
微信掃一掃