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簡(jiǎn)要描述：JWA蛋白抗體免 疫 原；KLH conjugated synthetic peptide derived from human JWA: 101-188/188
產(chǎn)品型號(hào)：GOY-01K1649廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：124產(chǎn)品分類
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JWA蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
JWA蛋白抗體 | JWA | GOY-01K1649 |
商品屬性：
英文名稱: JWA
中文名:JWA蛋白抗體
別 名；Addicsin; ADP
ribosylation like factor 6 interacting protein 5; Aip 5; Aip5; ARL 6
interacting protein 5; ARL6IP5 antibody Cytoskeleton related vitamin A
responsive protein; Dermal papilla derived protein 11; DERP 11; DERP11;
Glutamate transporter EEAC 1 associated protein; Glutamate transporter EEAC1
associated protein; GTRAP3 18; Hp 22; Hp22; HSPC 127; HSPC127; JM 5; JM5; JMX;
PRA 1 domain family 3; PRA 2; PRA1 domain family 3; PRA2; PRAF 3; PRAF3;
Prenylated Rab acceptor protein 2; Protein JWa; Putative MAPK activating
protein PM27; PRAF3_HUMAN.
研究領(lǐng)域；細(xì)胞生物 免疫學(xué) 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞分化
抗體來(lái)源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；22kDa
細(xì)胞定位；細(xì)胞漿 細(xì)胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human JWA: 101-188/188
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
JWA is a four-transmembrane environmental
responsive protein which binds to the CC chemokine recepor 5 (CCR5), a major
co-receptor for human immunodeficiency virus (HIV). JWA is involved in
environmental stress-responsive pathways in K562 cells, an erythroleukemia cell
line derived from patients with chronic myeloid leukemia. Environmental
stressors to K562 cells such as heat shock, a higher temperature than the
ideal body temperature of the organism from which the cell line was derived,
and oxidative stress, the production of oxygen-centered free radicals,
regulate and increase the expres-sion of JWA. This response to environmental
stressors suggests similiarity of JWA to heat shock protein 70 (HSP70), which
is upregulated by heat stress and toxic chemicals. Regulates intracellular concentrations of taurine
andglutamate. Negatively modulates SLC1A1/EAAC1 glutamate transportactivity
by decreasing its affinity for glutamate. May be involvedin membrane traffic
(By similarity). |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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