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簡(jiǎn)要描述：ING4抗體免 疫 原；KLH conjugated synthetic peptide derived from human ING4: 21-120/249
產(chǎn)品型號(hào)：GOY-01K0285廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：134產(chǎn)品分類
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ING4抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
ING4抗體 | ING4 | GOY-01K0285 |
商品屬性：
英文名稱: ING4
中文名:ING4抗體
別 名；Brain my036
protein; Candidate tumor suppressor p33 ING 1 homolog; Candidate tumor
suppressor p33 ING-1 homolog; Candidate tumor suppressor p33 ING1 homolog;
D6Wsu147e; D6Xrf92; ING 1 like protein; ING 4; ING-1 like protein; ING-4; ING1
like protein; ING4; ING4_HUMAN; Inhibitor of growth family member 4; Inhibitor
of growth family member 4 long isoform; Inhibitor of growth protein 4;
MGC12557; my036; p29 ING 4; p29 ING-4; p29 ING4; p29ING4; My036; inhibitor of
growth protein 4 isoform 1.
研究領(lǐng)域；腫瘤 發(fā)育生物學(xué) 染色質(zhì)和核信號(hào) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；27kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ING4: 21-120/249
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene encodes a tumor suppressor protein that
contains a PHD-finger, which is a common motif in proteins involved in
chromatin remodeling. This protein can bind TP53 and EP300/p300, a component
of the histone acetyl transferase complex, suggesting its involvement in the
TP53-dependent regulatory pathway. Multiple alternatively spliced transcript
variants have been observed that encode distinct proteins. [provided by
RefSeq, Jul 2008]. Component of the HBO1 complex which has a histone
H4-specific acetyltransferase activity, a reduced activity toward histone H3
and is responsible for the bulk of histone H4 acetylation in vivo. Through
chromatin acetylation it may function in DNA replication. May inhibit tumor
progression by modulating the transcriptional output of signaling pathways
which regulate cell proliferation. Can suppress brain tumor angiogenesis
through transcriptional repression of RELA/NFKB3 target genes when complexed
with RELA. May also specifically suppress loss of contact inhibition elicited
by activated oncogenes such as MYC. Represses hypoxia inducible factor's
(HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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