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簡要描述：白細胞介素增強子結(jié)合因子3抗體免 疫 原；KLH conjugated synthetic peptide derived from human ILF3: 1-100/894
產(chǎn)品型號：GOY-01K5087廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：159產(chǎn)品分類
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白細胞介素增強子結(jié)合因子3抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
白細胞介素增強子結(jié)合因子3抗體 | ILF3 | GOY-01K5087 |
商品屬性：
英文名稱: ILF3
中文名:白細胞介素增強子結(jié)合因子3抗體
別 名；CBTF; Double stranded
RNA binding protein 76; Double-stranded RNA-binding protein 76; DRBF; DRBP76;
ILF3; ILF3_HUMAN; Interleukin enhancer binding factor 3; Interleukin
enhancer-binding factor 3; M phase phosphoprotein 4; M-phase phosphoprotein 4;
MPHOSPH4; MPP4; NF AT 90; NF-AT-90; NF110; NF90; NFAR; Nuclear factor
associated with dsRNA; Nuclear factor of activated T cells 90 kDa; Nuclear
factor of activated T-cells 90 kDa; TCP80; Translational control protein 80
研究領域；細胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 轉(zhuǎn)運蛋白 表觀遺傳學
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產(chǎn)品應用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；95kDa
細胞定位；細胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ILF3: 1-100/894
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene encodes a double-stranded RNA (dsRNA)
binding protein that complexes with other proteins, dsRNAs, small noncoding
RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein
was first discovered to be a subunit of the nuclear factor of activated
T-cells (NFAT); a transcription factor required for T-cell expression of
interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the
larger of which is the product of this gene. These proteins have been shown
to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of
NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA
stabilization. In contrast, an isoform (NF110) of this gene that is
predominantly restricted to the nucleus has only minor effects on cell growth
when its levels are reduced. Alternative splicing results in multiple
transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2008] May facilitate double-stranded RNA-regulated gene
expression at the level of post-transcription. Can act as a translation
inhibitory protein which binds to coding sequences of acid beta-glucosidase
(GCase) and other mRNAs and functions at the initiation phase of GCase mRNA
translation, probably by inhibiting its binding to polysomes. Can regulate
protein arginine N-methyltransferase 1 activity. May regulate transcription
of the IL2 gene during T-cell activation. Can promote the formation of stable
DNA-dependent protein kinase holoenzyme complexes on DNA. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術(shù)服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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