歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！
咨詢電話：18321818584歡迎來(lái)到上海谷研實(shí)業(yè)有限公司網(wǎng)站！咨詢電話：18321818584
簡(jiǎn)要描述：羥基類固醇(17β)脫氫酶4/17β-HSD4抗體注意事項(xiàng)；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品型號(hào)：GOY-01K1680廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問(wèn) 量：135產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
羥基類固醇(17β)脫氫酶4/17β-HSD4抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
羥基類固醇(17β)脫氫酶4/17β-HSD4抗體 | HSD17B4 | GOY-01K1680 |
商品屬性：
英文名稱: HSD17B4
中文名:羥基類固醇(17β)脫氫酶4/17β-HSD4抗體
別 名；hydroxysteroid
(17-beta) dehydrogenase 4; 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase; 17 beta HSD 4; 17 beta HSD IV; 17 beta hydroxysteroid dehydrogenase
4; 17-beta-HSD 4; 17-beta-hydroxysteroid dehydrogenase 4; 17beta estradiol
dehydrogenase type IV; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24
enoyl CoA hydratase antibody 3-alpha; 7-alpha; Beta hydroxyacyl dehydrogenase;
Beta keto reductase; D 3 hydroxyacyl CoA dehydratase; D bifunctional protein; D
bifunctional protein peroxisomal; D-bifunctional protein; DBP; DHB4_HUMAN; EDH17B4;
Enoyl-CoA hydratase 2; Hsd17b4; MFE 2; MFE-2; MPF-2; Multifunctional protein 2;
Peroxisomal multifunctional enzyme type 2; Peroxisomal multifunctional protein
2; SDR8C1; Short chain dehydrogenase/reductase family 8C member 1; 17β-HSD4.
研究領(lǐng)域；腫瘤 心血管 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 線粒體
抗體來(lái)源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, Guinea Pig, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；47/80kDa
細(xì)胞定位；細(xì)胞漿 線粒體
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human HSD17B4 Enoyl-CoA hydratase 2:
521-620/736
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
17Beta-HSD4 (17Beta-hydroxysteroid dehydrogenase
type 4) is also known as peroxisomal multifunctional enzyme/protein 2
(MFE-2/MFP-2), D-bifunctional enzyme or 17-Beta Estradiol dehydrogenase type
IV. It belongs to the 17Beta-HSD family of proteins that regulate the
availability of steroids within various tissues throughout the body.
17Beta-HSD4 inactivates Estradiol through its oxidative activity but it is
primarily involved in peroxisomal fatty acid and cholesterol Beta-oxidation.
It has a multi-domain structure: the dehydrogenase domain is fused to a
hydratase and a lipid transfer domain. 17Beta-HSD4 is a target protein of
chromeceptin and it is essential for the downstream activation of Stat6.
17Beta-HSD4-deficient patients exhibit Zellweger-like syndrome and die within
the first year of life. They display neuronal migration defects, facial
dysmorphisms, severe hypotonia and convulsions in the neonatal period. |
多克隆抗體制備：
我公司合成抗原，保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
產(chǎn)品咨詢
聯(lián)系人：銷售部
地址：上海市嘉定區(qū)澄瀏公路52號(hào)盛創(chuàng)企業(yè)
郵箱：3004918891@qq.com
手機(jī)：18321818584 / 15026555973歡迎您關(guān)注我們的微信了解更多信息
掃一掃電話
微信掃一掃