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著絲粒蛋白K/FKSG14抗體
產品名稱 | 英文名稱 | 貨號 |
著絲粒蛋白K/FKSG14抗體 | Centromere protein K | GOY-01K1860 |
商品屬性：
英文名稱: Centromere protein K
中文名:著絲粒蛋白K/FKSG14抗體
別 名；AF5 alpha; AF5alpha;
B130045K24Rik; BB232189; C530004N04Rik; CENP K; CENPK; Centromere protein K;
Centromeric protein K; FKSG 14; ICEN 37; ICEN37; Interphase centromere complex
protein 37; Leucine zipper protein FKSG14; OTTHUMP00000161888; P33; Protein AF
5alpha; Protein AF5alpha; Solt; Solzt; SoxLZ/Sox6 binding protein Solt;
SoxLZ/Sox6 leucine zipper binding protein; CENPK_HUMAN.
研究領域；細胞生物 免疫學 表觀遺傳學
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；32kDa
細胞定位；細胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human FKSG14/Centromere protein K:
51-150/269
亞 型；IgG
純化方法；affinity
purified by Protein A
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
FKSG14, also known as CENPK (centromere protein K)
is a component of the CENPA-CAD (nucleosome distal) complex. It may be
involved in incorporation of CENPA into centromeres and is required for
proper kinetochore function, mitotic progression and chromosome segregation.
May be involved in incorporation of newly synthesized CENPA into centromeres
via its interaction with the CENPA-NAC complex. Acts in coordination with
CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore. FKSG14
constitutively localized to centromeres throughout the cell cycle. There are
3 isoforms produced by alternative splicing. Function: Component of the CENPA-CAD (nucleosome distal)
complex, a complex recruited to centromeres which is involved in assembly of
kinetochore proteins, mitotic progression and chromosome segregation. May be
involved in incorporation of newly synthesized CENPA into centromeres via its
interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1
to recruit the NDC80 complex to the outer kinetochore. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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